The Benchmark Scientific T3-0248G MultiCycler 248 is a dual-block thermal cycler from Benchmark’s MultiCycler T3 series. The MultiCycler 248 features 2 x 48 well blocks that accept 0.2 mL PCR tubes and strips, and flat or dome caps. The Benchmark Scientific T3-0248G MultiCycler 248 is designed for laboratories wanting flexibility in their applications. Benchmark’s MultiCycler Thermal Cyclers offer multiple, independent cycling blocks in a single unit. Both dual or triple models offer extremely fast cycling profiles, large touchscreen interfaces, self-adjusting heated lids, gradient capabilities, and an easy-to-use program wizard. All programming features are accessed from the 10-inch full-color touch screen. The screen can be angled towards the user when in use and then tucked away to save space. A program wizard guides users through the simple protocol setup process. Advanced programming features include gradient, adjustable ramp rates, and time increments and decrements. For multi-user labs, password protection prevents interference with an existing run. A USB interface provides unlimited program storage and easy transfer of protocols between MultiCycler machines. The Benchmark Scientific T3-0248G MultiCycler 248 has an auto-adjusting heated lid which prevents condensation and evaporation of samples. The lid temperature can be programmed, and when the blocking temperature is below 95°F, the lid automatically shuts off. Peltier units allow for exceptionally fast heating and cooling of the blocks. Temperature change is precisely and accurately controlled within tight tolerances by a proprietary algorithm that simulates sample temperature, resulting in fast runs and reproducible results. The wells are arranged in a 4 x 8 and 6 x 8 format, allowing for the use of PCR strips and tubes in both models. Each block is independently controlled.